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10.1007/s10585-014-9678-x 168

doi: 10.1177/147323000403200305

What your describing is not uncommon because methylation process is so complex & you may be deficient in other co-factors, such as B6, B2, Same, B12, etc Too much 5MTHF can drive overmethylation or dampen glutathione production and lead to agitation, irritability

Multi-peptide protocols require careful planning

Ipamorelin appears to elevate baseline GH secretion, while Mod GRF 1-29 may sustain pulsatile activity