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Semaglutide is instead eliminated predominantly through proteolytic degradation distributed across multiple tissues (no single organ dominates clearance), with minor renal excretion of metabolite fragments

It works by targeting the receptors in the brain for two different hormones, GIP and GLP-1, which the body produces after eating

The study included more than 17,000 adults with overweight or obesity who did not have diabetes

Semaglutide is a novel type of diabetic medication known as a GLP-1 agonist

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