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Some providers keep patients at 1.0 mg if glycemic control is achieved, never reaching the higher tiers

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However, experts say patients discontinuing these medications may experience sharp metabolic shifts

Post-discontinuation, 19.6 % restarted the original medication, while 35 % adopted another option: alternative medication (27.4 %), healthcare visit for lifestyle modification (13.7 %), and metabolic and bariatric surgery (0.6 %)

Semaglutide, meanwhile, is still tagged as being in shortage by the FDAeven if all doses of Wegovy and Ozempic are marked as available on the regulators website

Using more water (e.g., 4mL) dilutes it further, requiring a larger volume per dose, which can be easier to measure precisely