doi: 10.1038/s41577-020-00478-8 158 MajTWangWCrespoJZhangHWangWWeiSet al
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The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
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It is generally accepted that neuronal 7nAChR plays a significant role in a series of cellular responses, including but not limited to calcium influx, synaptic plasticity, neurotransmitter release, and excitatory transmission, and significantly contributing to the development of dependency, learning, memory, and various other cognitive processes