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Additional information Edited by G Melino Supplementary Information accompanies this paper on Cell Death and Disease website Rights and permissions Cell Death and Disease is an open-access journal published by Nature Publishing Group

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[Abstract]2025 Jun 11;33(6):941-956.e10

A 2020 oncology review noted excessive glutathione intake may contribute to chemotherapy resistance in breast cancer patients

The other part of the hydrolyzed glutathione (GSH) molecule cysteinyl-glycine is transported back inside the cell and broken down further by nonspecific dipeptidases into cysteine and glycine ready providing substrates for glutathione (GSH) resynthesis

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