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Vitamin D/vitamin D receptor (VDR) signaling intersects inflammation, oxidative stress/mitochondrial injury, fibrogenic pathways, the reninangiotensinaldosterone system (RAAS), and the gutkidney axis, providing a biologic rationale for renoprotection

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21 Pharmacological agents such as COX-2 inhibitors, GHK-Cu (Copper Peptide), PTH (Parathyroid Hormone), alendronate, and alpha2-macroglobulin target specific molecular pathways involved in tissue repair

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