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History of unstable angina, myocardial infarction, coronary artery bypass graft surgery or percutaneous coronary intervention (such as angioplasty or stent placement) within 180 days of screening

Indication and important safety information [Internet]

Shuxiao explains

Its designed to increase the dose safely and reduce side effects

Bimagrumab to improve recovery after hip fracture in older adults: a multicentre, double-blind, randomised, parallel-group, placebo-controlled, phase 2a/b trial

The improvements in HbA1c and weight loss were also clinically meaningful, the former reflecting evidence from DCCT/EDIC 2,3 and the latter meeting the minimum weight loss (5%) needed for metabolic improvement 41