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They support fat metabolism, energy, and muscle preservation during active weight loss when used alongside a clinical program

[2] However, once stores are depleted, symptoms can include fatigue, weakness, constipation, loss of appetite, and neurological changes such as numbness, tingling, balance problems, and cognitive difficulties

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In addition to its role in maintaining a normal sleep-wake cycle, melatonin plays an important part in autonomic regulation, including blood pressure, pulse, and temperature, as well as immune response and glucose homeostasis

You can find additional explanations in the later sections of the article that will enhance your understanding

First, although it was a prospective multicenter trial, it was still a single-arm study without a placebo