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Vitamin D Individuals often take vitamin D3 supplements if they are not able to obtain adequate vitamin D from exposure to sunshine

Olpasiran and lepodisiran are GalNAc conjugates containing siRNAs that target the LPA gene, promoting RISC-mediated degradation of Apo(a) mRNA and preventing Lp(a) particle assembly in hepatocytes

The role of mTORC2 in the regulation of autophagy is less investigated than mTORC1

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Protects against signs of sun and environmental damage such as wrinkles, pigmentation and tanning

This work was partly supported by Grants-in-Aid from the Japan Society for the Promotion of Society (17K16958 to K.S., 17H04349 to T.N.)