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Description

Rather than targeting hormones or appetite pathways, it works inside the cell itself blocking an enzyme called NNMT that sits at the centre of how fat cells manage energy

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S.ZhangJ.et al (2020)

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These effects are generally short-term

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The highest prevalence of hemolytic crises in G6PD deficiency is in children ages 13 ( For example, crises may present as hyperbilirubinemia a buildup of bilirubin resulting from the breakdown of red blood cells and severe jaundice, which may require phototherapy ( Newborn screening for G6PD deficiency is not yet routine in the United States

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Eardley, I., et al

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Results vary based on factors such as dosage, frequency of administration, and individual response

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