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c , UMAP of sequenced DRG cells showing intermingled distribution of cells from control, EndoS treated autoantibodies and autoantibodies (Arthritis) combined with in vivo IFN block (IFNAR1 antibody)

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POTENTIAL MECHANISMS UNDERLYING THE DECLINE IN GH SECRETION WITH AGE Three hypothalamic factors regulate GH secretion: somatostatin (Somatotropin Release-Inhibiting Factor, SRIF), growth hormone-releasing hormone (GHRH), and ghrelin (11) (Figure 2)

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