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In aged mice, FOXO4-DRI treatment restored fur density, improved renal function, and increased physical activity levels, demonstrating functional rejuvenation through targeted senescent cell clearance

Clinical trials are needed to confirm safety and dosing

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Images: Examples of products linked to liver toxicity Symptoms and investigations Patients have experience various symptoms including: tiredness or malaise jaundice abdominal pain dark urine abnormal bruising Investigation results include abnormal liver function tests showing transaminitis with possible raised bilirubin and coagulopathy

doi: 10.18231/j.jchm.2021.030 24