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499,500,501,502,503,504,505 The DUB OTUD5 (DUBA) promotes RORt degradation by stabilizing the E3 ligase UBR5, highlighting the intricate regulation of Th17 cells by the UPS

Our study indicates the importance of IGF-1R in maintaining a balance between cell survival and apoptosis of GNE deficient cells that are of interest to be explored further for drug design in disorders associated with sialic acid deficiency

demonstrated that CNS leptin administration normalized myocardial fatty acid oxidation, and improved glucose oxidation and mitochondrial function in hearts of leptin-deficient ob/ob mice, and this effect was independent of caloric intake and reduction in body weight [24]

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Its leaf extract is known to have possessed strong antioxidant, antibacterial, and anti-breast cancer activity