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The sub-30-minute plasma half-life is the pharmacokinetic basis for twice-daily dosing, though no human study has confirmed this produces better outcomes

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Patients should be advised to contact their GP if neurological symptoms worsen or new symptoms develop despite treatment

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Cartilage and chondrocyte research that emerged after the obesity program ended, exploring AOD-9604's effects on osteoarthritis-relevant pathways in cartilage explants and synovial tissue models