Migraine has a significant genetic component, with heritability estimates ranging from 50 to 80% (Yeh et al., 2024
Sakamoto K., Iwasaki K., Sugiyama H., Tsuji Y., Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications.Mol
The absence of reliable non-invasive biomarkers represents a major gap in endometriosis diagnosis
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The upregulated genes were enriched in pathways associated with the cell cycle, cell proliferation, antioxidant stress, and energy metabolism
The pharmacological inhibitor of myoferlin can reduce the abundance of System X c - and GPX4 which trigger mitophagy and ROS accumulation culminating with lipid peroxidation and ferroptosis (Rademaker et al., 2022)