Treatment with inactive, negative control compounds ( 11 and 12 ), structurally related to the active inhibitors 1 - 10 , had minimal effect on the GSH/GSSG in treated worms
Anything else falls outside that legal lane
Because it takes time to increase glutathione production through diet, it can take months to feel the benefits
Although approximately 1 in 1500 patients exhibit signs of chronic liver injury in long-term prophylactic therapy, acute liver injury due to NFT is quite rare, with approximately 0.3 cases per 100,000 prescriptions (LiverTox 2020)
R., Rosenberg, S
More advanced disease may present with wet beriberi (dilated cardiomyopathy resulting in high-output heart failure and pulmonary edema) or Wernicke-Korsakoff syndrome, which is a combination of Wernicke encephalopathy (characterized by the triad of confusion, ataxia, and ophthalmoplegia) and Korsakoff syndrome (amnesia and confabulation)