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In the study by Neelakantan et al

Given the human trials in early 2000s showed no adverse events, despite using enormous doses, and the animal data corroborating this, many practitioners feel comfortable prescribing/recommending BPC-157 (I am not making such a recommendation)

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Selenium toxicity can be a problem, especially for animals living in or around a body of water in an area with high soil selenium levels

This is consistent with the peptides role in accelerating the resurfacing and regenerative processes that normally slow with age