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One of those negative impacts could be alopecia, or hair loss

However, more research is needed to support these claims

Combined with the anti-reflux benefits of weight loss, the long-term trajectory favors improvement

GLP-1 plays a central role in regulating appetite, blood sugar, and digestion, but in many people particularly those with obesity or metabolic dysfunction this hormonal signaling is impaired or insufficient to maintain a healthy weight

This phenomenon may be attributed to the markedly higher expression of PGC-1 in energy-demanding tissues such as the liver [59]

Notably, serum tGSH (but not serum cystine) levels were lower in mice with tumours than in mice without tumours (Extended Data Fig