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Some clinics and wellness centers offer package deals that can reduce the overall cost

Gastrointestinal adverse effects such as nausea, vomiting, diarrhea and constipation are the most common and arise from delayed gastric emptying and increased central satiety signaling[12]

Whilst orlistat works locally in the gut with minimal systemic absorption, Wegovy is absorbed into the bloodstream and acts centrally on the brain's appetite regulation centres, as well as slowing gastric emptying

Many patients experience reduced appetite and fluid intake when starting GLP-1 therapy, whilst the medicine's gastrointestinal effects including nausea and occasional vomiting can further affect hydration status

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Supplements like berberine have their own glucose-lowering effects