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2013:437576 Szukiewicz D, Szewczyk G, Pyzlak M, Stangret A, Bachanek M, Trojanowski S, Alkhalayla H, Wejman J (2018) Anti-inflammatory action of metformin with respect to CX3CL1/CX3CR1 signaling in human placental circulation in normal-glucose versus high-glucose environments

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However, there are still strategic timing considerations worth understanding