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Univariate statistical testing was conducted to identify differentially expressed metabolites

[14] Crabtree MJ, Channon KM

Search Strategy A comprehensive search of PubMed/MEDLINE and the Cochrane Central Register of Controlled Trials (CENTRAL) was performed from database inception through the final search date

Work closely with the FDA via meetings such as the pre-investigational new drug (IND) phase meetings, Type C meetings, and pre-NDA meetings to gain the FDAs input regarding the scope of its proposed studies

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