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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action As a copper chelator, GHK-Cu modulates over 4,000 human genes, upregulating those involved in tissue remodeling (e.g., collagen I, III) and downregulating pro-inflammatory pathways like NF-B

10.1016/s0021-9258(19)83730-4 42 KoiwaiK.InabaK.MorohashiK.EnyaS.AraiR.KojimaH.et al (2020)

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One percentage cannot prove all four identities, separate quantities, copper coordination, ratio, aggregation, uniformity or stability