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17 In a randomized controlled study of adults with overweight or obesity and traits of metabolic syndrome, fiber supplementation with energy restriction improved body weight, body mass index, fat mass, visceral fat, lipid profile, and inflammatory markers

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Similarly, the large jump from 1.0mg to 1.7mg can be split into 1.25mg followed by 1.5mg followed by 1.7mg for people with sensitive gastrointestinal systems

Regaining weight after stopping the medication is common unless supported by ongoing changes

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