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"A lot of times, people have worked hard in therapy to be able to put those thoughts onto the back burner so they can be active and productive, and these thoughts arent impacting their daily functioning, says Smith

Preclinical studies demonstrate GIP signaling can attenuate GLP-1-induced nausea pathways

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Neuropsychopharmacology 46 , 288296 (2021)

Human trials are ongoing, but even modest effects in opioid use disorder could be clinically meaningful given the favorable safety profile of GLP-1 drugs compared with existing treatments

Many patients explore combination therapy hoping to accelerate results