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Traditional medicine systems used berberine-containing plants for various purposes long before metabolism became the modern headline

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The portion also formed alkyl interactions with residues Phe439, Phe344, in addition, the compound formed van der Waals interactions and was more surrounded by hydrophobic residues than hydrophilic residues of the enzyme's active site [54]

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TB-500 : A common maintenance protocol is 2.5 mg once per month