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By disrupting the interaction between FOXO4 and p53, FOXO4-DRI reactivates apoptosis in aged cells, clearing them from tissues and promoting systemic rejuvenation (1, 2)
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Doses vary from 1,000 to 4,500 mg per day
Adems, aumenta la secrecin de insulina en presencia de glucosa, al tiempo que suprime el glucagn, reduciendo la produccin heptica de glucosa
Dose titration represents the most important preventative strategy