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Labeled uses include treatment of type 2 diabetes as an addition to diet and exercise, and use in certain adults with heart failure or chronic kidney disease to reduce defined risks

This finding supports the peptides suitability for subcutaneous administration protocols

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Measuring total GLP-1 levels in vivo revealed that the effect elicited by the SSTR5a on glucose tolerance most likely is due to increases in GLP-1 secretion, which is in line with the findings by Farb et al