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The Nrf2sMAF heterodimer binds to the antioxidant response element (ARE), which leads to the transcription of genes encoding antioxidant and detoxification enzymes such as SOD, CAT, GP X , heme oxygenase 1 (HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), which protect cells from oxidative stress and toxins (19, 124126) (Figure 3)

Thorough documentation of the symptom constellation guides code specificity and supports medical necessity for electrodiagnostic studies

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Fertil Steril 98(3):511519