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doi: 10.1158/0008-5472.CAN-07-6771

A lack of antioxidants, such as glutathione, could make liver cell death worse, exacerbating the effects of liver conditions

Schwartz and Bhaskaran (University of Texas Medical Branch) demonstrated collagen synthesis increases in fibroblast cultures

Key pathways affected by folate include one-carbon metabolism and the transsulfuration pathway, both essential for proper neurodevelopment

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The SURMOUNT-4 trial (Aronne 2023, JAMA) showed that adults who stopped tirzepatide after 36 weeks regained an average of 14.0% of body weight over the next 52 weeks, while those who continued tirzepatide lost an additional 5.5% a 19.4% between-group difference