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The first, normally the larger one, is labeled maximally at 24 hours and is of hepatic origin, chiefly from the heme of cytochrome P450, but also from other hemoproteins ( 192 )

Braz J Med Biol Res 25(2):129134 [PubMed] [Google Scholar] Grosso LM, Bracken MB (2005) Caffeine metabolism, genetics, and perinatal outcomes: a review of exposure assessment considerations during pregnancy

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Adding 2 ml of BAC water creates a concentration of 2,500 mcg/ml, meaning each 250 mcg dose requires drawing 10 units (0.1 ml) on a U-100 syringe