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Although RAAS inhibitors slows estimated glomerular filtration rate (eGFR) decline and reduces the relative risk of kidney failure by approximately 20%, substantial residual risk remains [9]

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These incretin-based medications work by mimicking naturally occurring hormones that enhance insulin secretion, suppress glucagon release, slow gastric emptying, and reduce appetite through central nervous system pathways

doi: 10.3390/nu16010172