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The interest is high because, as Palatins CEO noted, PDE5i non-response represents a substantial unmet need these drugs account for ~$4 billion in sales, yet up to 40% of ED patients dont respond adequately

Nslund J, Schierhorn A, Hellman U, Lannfelt L, Roses AD, Tjernberg LO et al (1994) Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging

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The covariates used in the calculation of propensity scores through multivariable logistic regression are listed in Table 1