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An agonist is a drug that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally binds to the receptor

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They met four times (visits 25) for 1 hour each to discuss diet, exercise, and behavior modification based on recommendations in the Diabetes Prevention Program ( 2.4 Study outcomes All outcome measures were collected at baseline and after 20 weeks, with analyses adjusted for baseline values