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Notably, tirzepatide has been associated with dose-dependent increases in adiponectin and reductions in MASH-related biomarkers, including ALT, cytokeratin-18, and procollagen III, in patients with type 2 diabetes [75]

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doi: 10.3390/cimb47040285 [DOI] [PMC free article] [PubMed] [Google Scholar] 129.Garca-Casares N, Gonzlez-Gonzlez G, De La Cruz-Cosme C, et al

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Patients should mark the date of first use on their pen to track this 6-week window accurately