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placebo), symptom severity categories, and their interaction (Table 4)

Glucuronidation (50-60%) - SAFE Primary detoxification pathway in adults Makes acetaminophen water-soluble for excretion INCREASES during pregnancy but cannot compensate for other pathway changes Severely underdeveloped in fetuses/newborns 2

Tumor volume over time (WT, n = 7

USAGE -

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