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For many patients, tirzepatide may be used as a long-term or even chronic therapy, much like medications for high blood pressure or cholesterol

Both of these factors highlight the likely impact of high costs of these medications (2000 Euros per year for the lowest dose of semaglutide as of June 2025), which is an important barrier to treatment for many people

Some individuals may experience fatigue and weakness solely from semaglutide administration

Aetna (CVS Caremark) makes Wegovy preferred on commercial plans with a stricter BMI 35 threshold

Some people describe being able to make food decisions without feeling like they are fighting themselves all day

Never freeze semaglutide If your semaglutide pen has ever been frozen, throw it away