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Phase Split option Daily dose 50 mg morning + 50 mg midday Notes Some sources prefer split AM dosing because the plasma half-life is short (about 4 to 7 hours in rodent PK)

This means AOD 9604 can be used for extended periods without diminishing returns from antibody-mediated inactivation

However, understanding safety data in context remains essential

[DOI] [PubMed] [Google Scholar] 7.Puri M, Kaur L, Walia GK, Mukhopadhhyay R, Sachdeva MP, Trivedi SS, Ghosh PK, Saraswathy KN