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C.AsanoE.JuhszC.MuzikO.ShahA.et al (2005)

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Whilst improved glycaemic control is the goal, avoiding large and rapid HbA1c reductions may reduce the risk of early worsening in patients with existing retinopathy

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Ania Jastreboff at Yale randomized 338 adults with obesity to placebo or one of four retatrutide doses (1 mg, 4 mg, 8 mg, or 12 mg) once weekly for 48 weeks