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Harrison SA, Marri SR, Chalasani N, et al

Nausea was reported in 44% of Wegovy-treated adults compared with 16% of placebo-treated adults, and these reactions were most often reported during dose escalation

It also suppresses IL-1, IL-6, IL-10, and TNF- [163]

Left panel: n = 3, p = 0.0143

Huerta, A.E., Navas-Carretero, S., Prieto-Hontoria, P.L., Martnez, J.A

The mechanisms behind GLP-1-related headaches are not fully understood, but likely involve changes in blood sugar levels (especially during early treatment when insulin sensitivity improves rapidly), dehydration from reduced fluid intake or GI losses, and the central nervous system effects of GLP-1 receptor activation, since GLP-1 receptors exist in the brain