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Nebiolo F, Bergia R, Bommarito L, Bugiani M, Heffler E, Carosso A, et al

demonstrated that treatment of AR mice with geniposide reduced IgE, IL-4, IL-5, and IL-17 levels and increased the IL_2 and IFN- levels in serum, and reduced CD4 + T cells and Foxp3 cell population in the spleen tissue (Zhang et al., 2019)

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Oxidative stress caused by ROS and other free radicals/oxidants plays an important role in the pathogenesis of atherosclerosis, diabetes, ischemic stroke and related central nervous system diseases (36,37)

L-ergothioneine is a powerful antioxidant that can help protect the brain and nervous system from damage

Available from: Hibler EA, Zhu X, Shrubsole MJ, Hou L, Dai Q