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Thesis, Massey University, 1979

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(Mayo Clinic) Diet: creates the calorie deficit Exercise: increases energy expenditure, improves body composition, supports long-term maintenance Mayo Clinic specifically notes that combining regular activity with healthy eating is best for reaching and maintaining a healthy weight

In the same trial, those on oral semaglutide lost an average of 4.7 kg (approximately 10 lbs) versus 3.8 kg (approximately 8 lbs) with empagliflozin from baseline to week 52 in weight

While "fasted" is ideal, "regularly" is mandatory