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Am J Ophthalmol 2001;132:19-26

8 Remaining Questions and Knowledge Gaps There is strong evidence that synovitis drives worse outcomes in osteoarthritis, contributing to more severe and persistent pain, heightened pain sensitization, faster structural deterioration, and an increased need for joint replacement

The article says qualified provider evaluation is required, with particular attention to any history of thyroid cancer, pancreatitis or severe kidney disease, and to pregnancy or breastfeeding

Peptide therapy is defined as the therapeutic use of peptide-based compounds

doi: 10.1111/j.1365-2230.2011.04142.x 91 JadejaSDMansuriMSSinghMPatelHMarfatiaYSBegumR

after reconstitution, refrigerate at 28 C (35.646.4 F) for up to 4 weeks