Chronic studies in rats given 200 mg/kg body weight per day for 104 weeks, dogs given 20 mg/kg PO x 84 days, cats given 40-65 mg/kg for 118 days did not produce any signs of toxicity (blood testing, liver histology)
Minerva Urol Nefrol 2010;62:213218
99, e22039
BMSC-Exos GATA4 inhibited ferroptosis through the upregulation of miR-330-3p, which negatively regulates BAP1, thereby preventing the opening of the mitochondrial permeability transition pore and subsequent mitochondrial dysfunction
Key ingredients used in the collection include: Bioadaptive Botanical Complex (rhodiola, maral root, Siberian ginseng, chaga mushroom and resurrection plant) a blend of bioadaptive botanical extracts from plants that survive in extreme climates and use the same properties to help skin bounce back from environmental stressors
Across all trials, the side effect profile of AOD 9604 was described as indistinguishable from placebo