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In glyoxalse system, increased activities of glyoxalse II (which is a GSH dependent enzyme) and enhanced GSH level contributed to reduce toxic methylglyoxal level (Nahar et al

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To assess the functional activity of each variant, we performed SRE-luciferase assays on HEK293 cells overexpressing each variant, followed by DOP activation by its agonists deltorphin II (DII) or DPDPE during 5 hours

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