doi: 10.1182/blood.2020009404 116 CriscitielloMFKraevILangeS
Dose adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function or during acute illness to minimize the risk of hypoglycemia or hyperglycemia [see Warnings and Precautions (5.3)]
Consulting with a qualified healthcare professional is imperative to evaluate suitability and guarantee secure administration, says Dr Chiranjiv Chhabra
Culig Z, Hobisch A, Cronauer MV, Radmayr C, Hittmair A, Zhang J, et al
Our results highlight the opportunity for pharmacogenetics and precision medicine approaches applied to GLP1 medication
"The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms." In the UK, the most commonly used GLP-1 therapies are Novo Nordisk's semaglutide-based Ozempic for diabetes and Wegovy for obesity, as well as Eli Lilly's Mounjaro (tirzepatide), which are all given as weekly injections
