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doi: 10.1016/j.exer.2005.06.013

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Moreover, excessive glucocorticoid activity, induced by chronic HPA axis activation, can foster insulin resistance, increase lipolysis, and raise serum levels of LDL-C, TC, and TGs (308)

Lilly said in December that in a Phase 3 clinical trial, patients taking the highest dose of the experimental injection lost nearly 29% of their body weight on average after about 16 months more than has been seen with any GLP-1 drug currently on the market

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