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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

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Externt testad av ett oberoende EU-laboratorium

doi: 10.1523/JNEUROSCI.4703-13.2014

This proposition arises mainly from their low or absent glutaminase co-activity, which decreases off-target cytotoxicity and subsequent inflammatory immune activation