does semaglutide cause hormonal changes Exploring beyond numeric weight loss: The metabolic effects of Dermal Hypersensitivity Reaction to Semaglutide:

Weight loss itself can shift thyroid hormone requirementsas body composition changes, the volume of distribution for thyroid medications shrinks, potentially causing hormone levels to rise

doi: 10.1136/thoraxjnl-2020-214756 24 FreislingHSeyed KhoeiNViallonVWagnerK-H

doi: 10.3389/fnins.2013.00181 35 HendershotCSBremmerMPPaladinoMBKostantinisGGilmoreTASullivanNRet al

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Clinical trial data suggests comparable GI side effect profiles, though some patients who cannot tolerate one medication do better on the other due to individual receptor sensitivity differences