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It has to be underlined that, while current evidence of GLP-1RAs efficacy on PsD-related comorbidities relies on solid systematic reviews, RCTs, and large cohort studies, their potential role in rheumatologic disorders, particularly in PsD, remains largely unexplored

B and C, DPP-4 inhibitors fitting into the DPP-4 catalytic site, where they interact with critical amino acid residues, including Phe357, Tyr547, Glu205, and Glu206 (87)

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The role of glycogen synthase kinase-3 in insulin resistance and type 2 diabetes