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Sermorelin and GHRP-2, both peptides with pituitary supporting effects, o perate by triggering the release of endogenous natural growth hormone from the pituitary gland

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PYY 136 is a gut hormone that binds to the Y1-R in pancreatic islets and central nervous system (CNS) nuclei that control appetite regulation in the brain including the brainstem area postrema (AP) and nucleus tractus solitarius (NTS), where it has an orexigenic effect 18

Numbers indicate mean values of LAG-1 level for each genotype (in blue) and numbers in bracket shows the sample size